Hydroformylation

Brochures, Flyers and Other Literature

4/03 Dowpharma Announces New Capabilities in Asymmetric Hydroformylation for Pharmaceutical Applications

Asymmetric Hydroformylation – New Developments in Asymmetric Hydroformylation  (104 KB PDF)

Optically active 3,4-diazaphospholane ligands and their application in asymmetric hydroformylation and allylic alkylation reactions (perspective) (477KB PDF)  (478 KB PDF)

Hydroformylation at Dowpharma: Extending a Proven Capability (602 KB PDF)

Dowpharma Scientific Publications
Please find detailed a synopsis of the papers and publications on Hydroformylation that scientists from Dowpharma^SM have published and contributed to since 1998. Due to copyright law we are unable to reproduce the papers online. As such we have quoted the publication reference.

Evaluation of Asymmetric Hydrogenation Ligands in Asymmetric Hydroformylation Reactions. Highly Enantioselective Ligands Based on Bis-phosphacycles. 
Axtell, A. T.; Klosin, J.; Abboud, K. A.  Organometallics,  2006, 25, 5003-5009.

Developing a Ligand Toolbox for Asymmetric Hydroformylation.
Lennon, I.; Rand, C. Speciality Chemicals Magazine. 2005, 25, 50-51.

Synthesis of Biologically Active Amines via Rhodium-Bisphosphite-Catalyzed Hydroaminomethylation.
Briggs, J. R.; Klosin, J.; Whiteker, G. T.; Org. Lett. 2005, 7, 4795-4798.

Highly Regio- and Enantioselective Asymmetric Hydroformylation of Olefins Mediated by 2,5-Disubstituted Phospholane Ligands.
Axtell, A. T.; Cobley, C J.; Klosin, J.; Whiteker, G. T.; Zanotti-Gerosa, A.; Abboud, K. A. Angew. Chem. Int. Ed. 2005, 44, 5834-5838.

Optically Active 3,4-diazaphopholane Ligands and Their Application in Asymmetric Hydroformylation and Allylic Alkylation Reactions (perspective).
Landis, C. R.; Rand, C. L.; Klosin, J. Chimica Oggi; Chemistry Today. Chiral Technologies Today supplement 2005, pages 12-16.

Highly Active, Regioselective, and Enantioselective Hydroformylation with Rh Catalysts Ligated by Bis-3,4-diazaphospholanes
Clark, T. P.; Landis, C. R.; Freed, S. L.; Klosin, J.; Abboud, K. A. J. Am. Chem. Soc. 2005, 127, 5040-5042.

Synthesis and Application of a New Bisphosphite Ligand Collection for Asymmetric Hydroformylation of Allyl Cyanide
Cobley, C J.; Gardner, K.; Klosin, J.; Praquin, C.; Hill, C.; Whiteker, G. T.; Zanotti-Gerosa; Petersen, J. L.; Abboud, K. A. J. Org. Chem. 2004, 69, 4031-4040.

Parallel Ligand Screening on Olefin Mixtures in Asymmetric Hydroformylation Reactions
Cobley, C. J.; Klosin, J.; Qin, C.; Whiteker, G. T. Org. Lett. 2004, 6, 3277-3280.

HTS identifies new catalyst ligands for AHF reactions.
Cobley, C. J.; Gardner, K.; Klosin, J.; Lennon, I. C.; Rand, C.; Whiteker, G.T.; Zanotti-Gerosa, A. Sp2, 2003, 2, 28.

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